Characterization of HIV-1 uncoating in human microglial cell lines
Abstract Background After viral fusion with the cell membrane, the conical capsid of HIV-1 disassembles by a process called uncoating.Previously we have utilized the CsA washout assay, in which TRIM-CypA mediated restriction of viral replication is used to detect the state of the viral capsid, to study the kinetics of HIV-1 uncoating in owl monkey